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Comparison of Average Sales Prices and Average Manufacturer Prices: Results for the Third Quarter of 2025

Issued on  | Posted on  | Report number: OEI-03-26-00040

Report Materials

This memorandum summarizes the results of the Office of Inspector General’s (OIG’s) comparison of average sales prices (ASPs) and average manufacturer prices (AMPs) for the third quarter of 2025. By law, OIG must notify the Secretary of Health and Human Services if the ASP for a particular drug exceeds the drug’s AMP by 5 percent or more. If that threshold is met, the Secretary may disregard the drug’s ASP when setting the reimbursement amount and substitute the lesser of either the widely available market price or 103 percent of the AMP.