Skip Navigation
United States Flag

An official website of the United States government. Here's how you know >

U.S. Flag An official website of the United States government.
Change Font Size

Report (OEI-07-13-00220)

10-30-2014
Drug Compendia Publishers Maintain Transparent Processes for Evaluating Anticancer Drug Therapies and Identifying Potential Conflicts

Complete Report

Download the complete report

Adobe® Acrobat® is required to read PDF files.

Summary

WHY WE DID THIS STUDY

Federal law mandates that drug compendia publishers (publishers) that evaluate anticancer drug therapies maintain transparent processes for evaluating anticancer drug therapies and identifying potential conflicts of interest on the part of their staff. Medicare Parts B and D cover anticancer drugs for indications not approved by the Food and Drug Administration only if the drugs are supported by one or more of the four authorized compendia. Conflicts of interest on the part of compendia staff might result in anticancer drugs being included in the compendia that otherwise might not have been included.

HOW WE DID THIS STUDY

This study included (1) a review of each publisher's policies and procedures-as posted on its Web site-for evaluating anticancer drug therapies and for identifying potential conflicts of interest; (2) interviews with publishers' staff who were knowledgeable as to how potential conflicts were managed; and (3) an interview with CMS staff. Our review took place in September and October of 2013.

WHAT WE FOUND

We found that the each of the publishers of the four authorized compendia complied with Federal laws for maintaining a transparent process for evaluating anticancer drug therapies and identifying potential conflicts of interest. We also found that the number and nature of disclosures related to potential conflicts of interest varied across publishers.

WHAT WE CONCLUDE

All four publishers complied with Federal law to maintain a transparent process for evaluating anticancer drug therapies and identifying potential conflicts of interest among staff. Insufficient evaluation criteria and conflicts of interest among compendia staff could lead to anticancer drugs being inappropriately recommended for inclusion in a compendium. Because Medicare Parts B and D cover anticancer drugs supported by one or more of the four authorized compendia, transparency of publishers' policies helps safeguard against inappropriate Federal payments for these drugs and protects Medicare beneficiaries from being prescribed drugs for medically inappropriate uses.

I'm Looking For

Let's start by choosing a topic

Exclusions Database Report Fraud

Office of Inspector General, U.S. Department of Health and Human Services | 330 Independence Avenue, SW, Washington, DC 20201