This final report provides results of review of the National Institutes of Health (NIH) printing program made to determine whether the program was complying with laws and regulations applicable to the Government Printing Office's (GPO) requirements. The report notes the NIH did not report its monthly commercial printing activity to GPO as required. Also, the NIH did not always provide copies of printed publications to GPO for distribution to Federal Depository Libraries and for purposes of cataloging and indexing. Recommendations call for actions the NIH needs to take to meet the GPO's requirements. The NIH fully concurred with our recommendations.