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Department of Health and Human Services

Office of Inspector General -- AUDIT

"Review of Alleged Conflict-of-Interest In Institute of Medicine Study of the Adverse Consequences of Pertussis and Rubella Vaccines," (A-15-90-00054)

January 3, 1992

Complete Text of Report is available in PDF format (272 kb). Copies can also be obtained by contacting the Office of Public Affairs at 202-619-1343.


This final report responds to congressional concerns about allegations regarding conflicts-of-interest that could affect the credibility of a study of adverse consequences of pertussis and rubella vaccines. Our review identified conflicts-of-interest for two committee members. One individual was employed by a gateway.html fund that was fully supported by a DPT manufacturer. Another resigned after the Institute of Medicine Study learned that the person had made public statements in a legal deposition on the effects of DPT vaccines. We also found that NIH failed to assure the impartiality and objectivity of work performed under this advisory and assistance contract.